Concerned Parents  Report © is dedicated to reporting information and imparting knowledge to parents so they can empower their children to make the healthiest choice for their reproductive health - living a  chaste lifestyle


Hormone Therapy Trial Stopped Due to Increased Cancers and Heart Disease

Cancer and coronary risks of hormone therapy for postmenopausal women were found to outweigh the benefits of treatment.

  • The Women’s Health Initiative trial of estrogen plus progestin was halted as researchers realized the risks of hormone therapy exceeded its benefits. Healthy postmenopausal women ages 50-79 received either hormone therapy or a placebo. The trial stopped after 5.6 years of follow-up because the researchers found an increased risk of invasive breast cancer in participants that were taking the estrogen+progestin pills. In addition, women who received hormone therapy had a higher risk of coronary heart disease, stroke, and venous thromboembolism compared to participants taking placebo pills.   In the same study, however, the estrogen+progestin therapy was shown to lower the risks for hip fracture and colorectal cancer.1


1 Health Risks and Benefits 3 Years After Stopping Randomized Treatment With Estrogen and Progestin, JAMA Vol. 299 No. 9 March 5, 2008; pp. 1036-1045


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